Generic Filitra Professional (Vardenafil)

Introduction

Filitra Professional is a tablet that contains the phosphodiesterase-5 (PDE5) inhibitor vardenafil. It is indicated for the treatment of erectile dysfunction (ED) in adult males. The product is supplied in a 20 mg tablet form and belongs to the class of oral agents that enhance sexual response by improving blood flow to the corpora cavernosa. Vardenafil is the same active ingredient found in several brand-name products, and Filitra Professional provides a cost-effective alternative for patients who need reliable ED therapy. In addition to its approved role in ED, limited clinical research has explored other potential applications, which are discussed later.

What is Filitra Professional?

Filitra Professional is a pharmaceutical tablet that delivers a fixed dose of 20 mg vardenafil.

• Classification: Oral PDE5 inhibitor, used primarily for erectile dysfunction.
• Development history: Vardenafil was first approved by the U.S. Food and Drug Administration (FDA) in 2003 under the brand name Levitra. Since then, generic formulations have been produced worldwide.
• Manufacturer: The specific manufacturer of Filitra Professional is not disclosed publicly, but the product is produced under Good Manufacturing Practice (GMP) standards and distributed by licensed suppliers.

Filitra Professional contains the active compound vardenafil, the same molecule marketed under brand names such as Levitra and Staxyn. Our online pharmacy offers this generic alternative as an affordable treatment option for men with erectile dysfunction.

How Filitra Professional Works

Vardenafil selectively inhibits the enzyme phosphodiesterase-5 (PDE5) that degrades cyclic guanosine monophosphate (cGMP) in the smooth muscle of the penis. During sexual stimulation, nitric oxide released from nerve endings activates guanylate cyclase, increasing cGMP levels. Elevated cGMP causes smooth-muscle relaxation, allowing arterial blood to fill the corpora cavernosa, producing an erection. By blocking PDE5, Filitra Professional prolongs the cGMP signal, enhancing and maintaining erectile rigidity.

Key pharmacokinetic points:

• Onset of action: 30-60 minutes after oral intake.
• Peak plasma concentration: Approximately 1 hour.
• Duration of effect: Up to 4-5 hours, varying with individual metabolism.
• Elimination: Primarily hepatic metabolism via CYP3 A4; renal excretion accounts for a small proportion.

These characteristics make vardenafil suitable for use on an as-needed basis rather than continuous daily dosing.

Conditions Treated with Filitra Professional

Erectile Dysfunction (ED)

ED is the inability to achieve or maintain an erection sufficient for satisfactory sexual performance. Clinical trials involving thousands of men have demonstrated that vardenafil improves erection quality and sexual satisfaction compared with placebo. The drug is approved by the FDA, the European Medicines Agency (EMA), and numerous national regulatory agencies for this indication.

Why it works: By preserving cGMP, the medication enhances the natural physiological response to sexual arousal, addressing the vascular component of most ED cases.

Off-Label and Investigational Uses of Filitra Professional

While regulatory authorities have approved vardenafil only for erectile dysfunction, clinicians and researchers have examined additional scenarios:

• Pulmonary arterial hypertension (PAH). Small pilot studies suggest that PDE5 inhibition can lower pulmonary artery pressure. However, vardenafil is not approved for PAH and larger trials are required.
• Benign prostatic hyperplasia (BPH) symptom relief. Some investigations report modest improvement in lower-urinary-tract symptoms when combined with α-blockers, but evidence remains limited.
• Female sexual arousal disorder. Preliminary research has explored off-label use in women, yet results are inconsistent and safety data are insufficient.

These uses have not received formal approval from the FDA, EMA, or other health authorities. Any consideration of off-label treatment must occur under the direct supervision of a qualified healthcare provider.

Is Filitra Professional the Right Medication for You?

Filitra Professional is appropriate for adult men who:

• Have been diagnosed with erectile dysfunction of vascular or neurogenic origin.
• Experience intermittent sexual activity and prefer on-demand therapy.
• Do not have contraindications listed below.

Clinical scenarios favoring vardenafil:

• Need for a relatively rapid onset (30-60 minutes).
• Desire for a medication with a slightly shorter half-life than tadalafil, reducing the window of systemic vasodilation.

Patients with severe cardiovascular disease, uncontrolled hypertension, or those taking nitrates should avoid this medication. Individuals with hereditary retinal disorders (e.g., retinitis pigmentosa) are also contraindicated due to potential visual side effects.

Risks, Side Effects, and Interactions

Common

• Headache - usually mild, resolves within a few days.
• Facial flushing - transient warmth, particularly in the upper chest.
• Indigestion or dyspepsia - may improve with taking the tablet with food.
• Nasal congestion - occasional stuffy nose.

Rare

• Dizziness - often associated with orthostatic changes; advise standing slowly.
• Vision changes - bluish-tinted vision (chromatopsia) or increased light sensitivity; usually reversible.
• Priapism - prolonged erection lasting >4 hours; requires emergency care.

Serious

• Cardiovascular events - myocardial infarction, stroke, or sudden cardiac death in patients with pre-existing heart disease.
• Severe hypotension - especially when combined with nitrates or alpha-blockers.
• Severe allergic reactions - rash, itching, swelling, or difficulty breathing.

Drug-Drug Interactions

• Nitrates (e.g., nitroglycerin, isosorbide dinitrate) - concurrent use can cause profound hypotension; contraindicated.
• Alpha-blockers (e.g., tamsulosin, doxazosin) - may increase the risk of blood pressure drops; dose titration required.
• CYP3 A4 inhibitors (e.g., ketoconazole, erythromycin, ritonavir) - can raise vardenafil plasma levels, heightening side-effect risk; dose reduction to 10 mg is advised.
• CYP3 A4 inducers (e.g., rifampin, carbamazepine) - may reduce efficacy; consider alternative therapy.

Drug-Food Interactions

• High-fat meals - can delay absorption and reduce the speed of onset; patients seeking rapid effect should take the tablet on an empty stomach.
• Alcohol - moderate intake may be tolerated, but excessive consumption can impair erection and increase the likelihood of hypotension or dizziness.

Patients should disclose all medications, supplements, and over-the-counter products to their healthcare professional before starting Filitra Professional.

Use: Dosing, Missed Dose, Overdose

• Standard dosing: The recommended starting dose is 10 mg taken orally about 30-60 minutes before anticipated sexual activity. For most men, 20 mg is the optimal dose, but the tablet is marketed only in this strength; the dose can be reduced to 10 mg by taking a half tablet only if advised by a prescriber.
• Maximum frequency: Do not exceed one tablet within a 24-hour period.
• Missed dose: Filitra Professional is taken only when sexual activity is planned. If a dose is forgotten, simply omit it; do not take an additional tablet later that day.
• Overdose: Symptoms may include severe headache, hypotension, prolonged erection, or fainting. Seek immediate medical attention; there is no specific antidote, and treatment is supportive.

Practical precautions

• Avoid taking the tablet with grapefruit juice, as it can inhibit CYP3 A4 and raise drug levels.
• Do not operate heavy machinery or drive if you feel dizzy or light-headed after dosing.
• Store tablets at room temperature, protected from moisture and light; keep out of reach of children.

FAQ

• What should I do if I travel abroad with Filitra Professional?

  • Keep the tablets in their original packaging with the label visible. Carry a copy of the prescription or a physician’s note if required by customs.

• Can I take Filitra Professional with a high-protein snack instead of a fatty meal?

  • Protein-rich foods have minimal impact on absorption. The key is to avoid large amounts of fat, which can delay onset.

• How long does a 20 mg tablet remain stable in hot climates?

  • Vardenafil is chemically stable at temperatures up to 30 °C (86 °F) for several months. In hotter environments, store the medication, dry place or inside a insulated container.

• What inactive ingredients are in Filitra Professional tablets?

  • Typical excipients include microcrystalline cellulose, lactose monohydrate, magnesium stearate, and coating agents such as hypromellose. Exact composition may vary by manufacturer.

• Is a urine drug test affected by taking Filitra Professional?

  • Standard drug screens do not detect vardenafil. However, specialized testing for PDE5 inhibitors exists in some occupational health programs.

• Can the medication be crushed or chewed for faster absorption?

  • The tablet is formulated for oral swallow. Crushing or chewing may alter its release characteristics and is not recommended.

• What is the difference between Filitra Professional and longer-acting PDE5 inhibitors like tadalafil?

  • Vardenafil (Filitra Professional) has a shorter half-life (≈4-5 hours) and faster onset, while tadalafil provides up to 36-hour coverage, which may be preferable for spontaneous activity.

• Are there any age restrictions for using Filitra Professional?

  • The medication is approved for adult men 18 years and older. Use in younger patients has not been evaluated.

• How does renal impairment affect dosing?

  • In moderate renal impairment (creatinine clearance 30-50 mL/min), no dose adjustment is typically required. Severe impairment may increase exposure; a lower dose should be considered under medical guidance.

• Does Filitra Professional interact with herbal supplements such as St. John’s wort?

  • St. John’s wort is a CYP3 A4 inducer and can reduce vardenafil efficacy. Patients using such supplements should discuss alternatives with their clinician.

Glossary

Phosphodiesterase-5 (PDE5) inhibitor

A class of drugs that block the PDE5 enzyme, preventing the breakdown of cGMP and thereby promoting smooth-muscle relaxation in the penis.

cGMP (cyclic guanosine monophosphate)

A second messenger molecule that mediates vasodilation; higher levels lead to increased blood flow to erectile tissue.

Priapism

An erection lasting longer than four hours, unrelated to sexual stimulation, which can cause tissue damage if not treated promptly.

Cytochrome P450 3A4 (CYP3 A4)

A liver enzyme responsible for metabolizing many medications, including vardenlaf. Inhibitors or inducers of CYP3 A4 can alter drug levels.

Buying Filitra Professional from Our Online Pharmacy

Patients who encounter limited availability or high out-of-pocket costs at traditional pharmacies can obtain Filitra Professional through our online pharmacy. Our service offers several advantages:

• Affordable pricing: The generic formulation is priced near the manufacturer’s production cost, providing a cost-effective alternative to brand-name products.
• Verified quality: All tablets are sourced from licensed, GMP-certified suppliers that undergo rigorous quality-control testing before shipment.
• Discreet, reliable delivery: Orders are packaged in unmarked envelopes and dispatched via a tracked service, with standard shipping taking approximately 7 days (express) or up to 3 weeks (regular airmail) depending on the destination.
• International access: We operate as a pharmacy-broker service, collaborating with overseas licensed pharmacies to secure medications that may not be stocked locally. This model enables a broader selection while maintaining strict compliance with regulatory standards.

By choosing our online pharmacy, patients benefit from a secure, private, and economical pathway to obtain Filitra Professional when conventional options are unavailable or financially burdensome.

Disclaimer

The information provided about Filitra Professional is intended for general educational purposes only and does not substitute personalized medical advice. Treatment decisions, including those concerning off-label applications, should be made under the guidance of a qualified healthcare professional. Readers are presumed to be responsible adults capable of making informed health choices. Our online pharmacy supplies Filitra Professional for individuals who may face limited access through conventional pharmacies or who seek cost-effective generic alternatives. Always discuss any medication changes, potential interactions, or health concerns with a qualified provider before initiating, modifying, or discontinuing therapy.