Super Vidalista (Tadalafil with Dapoxetine)

Super Vidalista
Super Vidalista is a combination medicine designed for treatment of erectile dysfunction and premature ejaculation.
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Introduction

Super Vidalista is a fixed-dose oral tablet that combines two active ingredients: tadalafil, a phosphodiesterase-5 (PDE5) inhibitor, and dapoxetine, a short-acting selective serotonin-reuptake inhibitor (SSRI). The product is supplied in a 20 mg/60 mg strength and is intended for adult patients who experience erectile dysfunction (ED) and/or premature ejaculation (PE). Tadalafil is approved worldwide for erectile dysfunction and pulmonary arterial hypertension, while dapoxetine is approved in many regions for premature ejaculation. The combination aims to address both conditions simultaneously, offering a convenient therapeutic option for men whose sexual dysfunction involves impaired erection and reduced ejaculatory latency.

What is Super Vidalista?

Super Vidalista is a combination medication that contains the active compounds tadalafil and dapoxetine in a single pill. It belongs to the therapeutic groups of PDE5 inhibitors (for erectile dysfunction) and short-acting SSRIs (for premature ejaculation). The drug was developed to simplify treatment for men who suffer from both ED and PE, eliminating the need for two separate prescriptions.

The formulation is marketed under brand names such as Cialis (tadalafil) and Priligy (dapoxetine) when the ingredients are sold individually. Super Vidalista provides the same pharmacological action as these established products, but in a single, fixed-dose tablet. Our online pharmacy supplies this generic alternative at a cost-effective price, ensuring accessibility for patients who may face high out-of-pocket expenses with branded medicines.

How Super Vidalista Works

  • Tadalafil component - Tadalafil inhibits the enzyme phosphodiesterase-5, which degrades cyclic guanosine monophosphate (cGMP) in the smooth muscle of the corpus cavernosum. By preserving cGMP, tadalafil enhances nitric-oxide-mediated vasodilation, allowing increased blood flow into the penis during sexual stimulation. The effect typically begins within 30 minutes and can persist for up to 36 hours, providing a long therapeutic window.

  • Dapoxetine component - Dapoxetine selectively blocks the reuptake of serotonin, raising its synaptic concentration. Elevated serotonin levels delay the ejaculatory reflex by modulating spinal and supraspinal pathways that control emission. Dapoxetine’s rapid onset (1-2 hours) and short half-life (≈1 hour) mean it is taken on demand, close to sexual activity.

Together, the two agents act on complementary aspects of male sexual function: tadalafil improves the ability to achieve and maintain an erection, while dapoxetine extends intravaginal ejaculatory latency time (IELT).

Conditions Treated with Super Vidalista

Approved Indication Why Super Vidalista Is Effective
Erectile Dysfunction (ED) Tadalafil’s potent PDE5 inhibition restores normal penile hemodynamics, enabling satisfactory erections in response to sexual stimuli.
Premature Ejaculation (PE) Dapoxetine’s short-acting SSRI effect increases IELT, reducing the likelihood of uncontrolled ejaculation.
Combined ED + PE (in jurisdictions where the combination is authorized) Simultaneous modulation of erection and ejaculatory control addresses the dual-symptom profile without requiring two separate medications.

Off-Label and Investigational Uses of Super Vidalista

  • Benign Prostatic Hyperplasia (BPH) - Some clinical studies have explored tadalafil’s smooth-muscle relaxing properties for lower urinary tract symptoms associated with BPH. Evidence suggests modest symptomatic relief, but the combination with dapoxetine has not been evaluated for this purpose.

  • Female Sexual Dysfunction (FSD) - Low-dose PDE5 inhibitors have been investigated for improving genital blood flow in women. Dapoxetine’s effect on central serotonergic pathways is also of interest for reducing sexual arousal anxiety. These investigations remain preliminary, and the combination is not approved for female use.

  • Psychogenic Erectile Dysfunction - When ED has a strong anxiety component, the SSRI effect of dapoxetine may contribute to reduced performance anxiety. Limited case series report benefit, but robust randomized data are lacking.

All off-label applications are not officially approved by regulatory agencies such as the FDA or EMA. Patients should only consider these uses under direct supervision of a qualified healthcare professional, after a thorough risk-benefit assessment.

Is Super Vidalista the Right Medication for You?

Super Vidalista is most appropriate for adult men who:

  • Have a documented diagnosis of erectile dysfunction and desire a medication with a prolonged duration of action.
  • Experience premature ejaculation and prefer an on-demand short-acting SSRI.
  • Seek a single-tablet solution to treat both conditions concurrently.

Contraindications include:

  • Known hypersensitivity to tadalafil, dapoxetine, or any excipients in the tablet.
  • Use of nitrates (e.g., nitroglycerin) or recreational “poppers” (nitrites), which can cause severe hypotension when combined with tadalafil.
  • Severe uncontrolled hypertension, recent myocardial infarction, or advanced heart failure.
  • Concomitant use of medications that strongly inhibit CYP3A4 (e.g., ketoconazole, clarithromycin) or CYP2C19 (e.g., fluoxetine) may raise plasma levels of the active agents.

Patients with hepatic or renal impairment should consult a clinician for dose adjustment.

Risks, Side Effects, and Interactions

Common

  • Headache
  • Nasal congestion or flushing
  • Dyspepsia (indigestion)
  • Back pain or muscle aches (often related to tadalafil)
  • Nausea or mild dizziness

Rare

  • Visual disturbances (blurred vision, changes in color perception)
  • Priapism (prolonged erection lasting >4 hours)
  • Mood changes (elevated anxiety or depressive symptoms)

Serious

  • Severe hypotension, especially when combined with nitrates or potent vasodilators.
  • Cardiovascular events (myocardial infarction, stroke) in patients with pre-existing heart disease.
  • Allergic reactions (angioedema, urticaria, anaphylaxis).

Drug-Drug Interactions

  • Nitrates (e.g., isosorbide dinitrate) - potentiate hypotensive effect; contraindicated.
  • CYP3A4 inhibitors (ketoconazole, itraconazole, clarithromycin) - increase tadalafil exposure, raising risk of adverse events.
  • CYP2C19 inhibitors (fluoxetine, fluvoxamine) - elevate dapoxetine levels, potentially increasing side-effect burden.
  • Alpha-blockers (tamsulosin) - may cause additive blood-pressure lowering; monitor closely.

Drug-Food Interactions

  • High-fat meals can delay the onset of tadalafil’s effect but do not reduce overall efficacy.
  • Alcohol in excess may amplify flushing, dizziness, and hypotension; moderation is advised.

Use: Dosing, Missed Dose, Overdose

  • Standard dosing - The fixed-dose tablet contains 20 mg of tadalafil and 60 mg of dapoxetine. Most patients take one tablet 30 minutes to 2 hours before sexual activity. The medication may be taken with or without food. Do not exceed one tablet per 24-hour period.

  • Missed dose - If a dose is forgotten and sexual activity is not planned within the next 24 hours, simply discard the tablet and resume the regular dosing schedule. Do not double the dose to compensate for a missed tablet.

  • Overdose - Signs of overdose include pronounced hypotension, severe headache, prolonged erection, or marked dizziness. Seek immediate medical attention. Management is supportive; there is no specific antidote for either component.

  • Practical precautions - Avoid operating heavy machinery or driving until you know how the medication affects you. Limit alcohol consumption, as it can exacerbate vasodilatory effects. Store tablets below 30 °C, protected from moisture and direct sunlight.

FAQ

  • What should I do if I travel internationally with Super Vidalista?   Carry the medication in its original packaging with a copy of the prescription (if required). Most countries allow personal import of a 30-day supply for personal use, but verify local regulations before travel.

  • Can Super Vidalista be taken with a high-protein meal?   High-protein meals do not significantly affect absorption. Only very high-fat meals may delay the onset of tadalafil’s effect by up to 30 minutes.

  • What is the appearance of the Super Vidalista tablet?   The tablet is round, light blue, and imprinted with “20/60” on one side to denote the tadalafil/dapoxetine content.

  • Are there any inactive ingredients that could cause allergies?   Common excipients include lactose, microcrystalline cellulose, and magnesium stearate. Patients with known hypersensitivity to these substances should discuss alternatives with their clinician.

  • Will a drug test detect Super Vidalista?   Standard workplace drug panels do not test for tadalafil or dapoxetine. However, specialized testing could detect either compound if specifically requested.

  • Is Super Vidalista approved for use in women?   No. The combination is approved only for adult men with erectile dysfunction and/or premature ejaculation. Use in women remains investigational and off-label.

  • Can I store Super Vidalista in a humid climate?   The tablets should be kept in a dry environment, preferably in a sealed container. Excess humidity can degrade the active ingredients over time.

  • How long does the tablet remain effective after manufacturing?   The shelf life is typically 24 months from the date of manufacture, provided the product is stored under recommended conditions.

  • Does Super Vidalista interact with herbal supplements?   Certain supplements, such as St. John’s wort (a CYP3A4 inducer) or grapefruit juice (a CYP3A4 inhibitor), can alter plasma levels of tadalafil. Discuss any herbal product use with a healthcare professional.

  • What is the difference between Super Vidalista and taking the two drugs separately?   The combined tablet ensures a fixed dose ratio, simplifying dosing schedules and reducing the need for multiple prescriptions. Pharmacokinetic profiles are comparable to the individual agents taken together.

Glossary

Phosphodiesterase-5 (PDE5) Inhibitor
A class of drugs that block the enzyme responsible for breaking down cGMP, thereby enhancing blood flow to the penis during sexual arousal.
Selective Serotonin-Reuptake Inhibitor (SSRI)
A medication that increases serotonin levels in the brain by preventing its reabsorption, used here to delay ejaculation.
Intravaginal Ejaculatory Latency Time (IELT)
The measured interval from vaginal penetration to ejaculation; dapoxetine aims to increase this interval.

Buying Super Vidalista from Our Online Pharmacy

Patients who encounter limited availability, high out-of-pocket costs, or privacy concerns with traditional pharmacies can obtain Super Vidalista through our online pharmacy.

  • Affordable pricing - We purchase the medication close to manufacturer cost, passing savings directly to you.
  • Verified quality - All tablets are sourced from licensed, overseas pharmaceutical partners that meet international Good Manufacturing Practice (GMP) standards.
  • Discreet delivery - Packages are shipped in unmarked, secure envelopes, with optional express service (delivery within 7 days) or standard airmail (approximately 3 weeks).
  • Privacy-focused service - As a pharmacy broker, we handle all transactions confidentially, safeguarding your personal information throughout the ordering process.

Our online pharmacy offers a reliable, cost-effective pathway for accessing Super Vidalista when local options are insufficient or financially burdensome.

Disclaimer

The content presented about Super Vidalista is intended for general educational purposes only and does not replace professional medical evaluation. Treatment choices, including any off-label applications, must be made under the guidance of a qualified healthcare provider. Readers are presumed to be responsible adults capable of informed health decisions. Our online pharmacy provides access to Super Vidalista for individuals who may encounter limited availability through conventional pharmacies or insurance-based dispensing, and who are seeking a cost-effective generic alternative. Always consult your physician before initiating, modifying, or discontinuing any medication.

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