Super P-Force (Sildenafil with Dapoxetine)

Introduction

Super P-Force is a fixed-dose oral tablet that combines two pharmacologically active ingredients: sildenafil, a phosphodiesterase-5 (PDE5) inhibitor, and dapoxetine, a short-acting selective serotonin-reuptake inhibitor (SSRI). The product is supplied as a 100 mg/60 mg pill. Sildenafil has long been used to improve erectile function, while dapoxetine is approved in several regions for the treatment of premature ejaculation (PE). The combination is intended for adult men who experience both erectile dysfunction (ED) and PE, providing a single daily dose that addresses both conditions. The medication belongs to the classes of PDE5 inhibitors and short-acting SSRIs.

What is Super P-Force?

Super P-Force is a pharmaceutical tablet that contains the active compounds sildenafil (100 mg) and dapoxetine (60 mg) in a single formulation. The product is manufactured by a licensed pharmaceutical company that follows Good Manufacturing Practice (GMP) standards; specific corporate details are disclosed on the product label. It is classified as a combination therapy for sexual dysfunction in men.

The tablet is designed for oral administration and is marketed as a convenient alternative to taking two separate medications. Although the combination is not currently approved as a single branded product by the U.S. Food and Drug Administration (FDA) or the European Medicines Agency (EMA), each component has well-established regulatory status in its own indication.

How Super P-Force Works

Sildenafil works by inhibiting the enzyme phosphodiesterase-5, which normally degrades cyclic guanosine monophosphate (cGMP) in the corpus cavernosum of the penis. By preserving cGMP, sildenafil facilitates smooth-muscle relaxation and arterial inflow, leading to an erection in response to sexual stimulation. The onset of action typically occurs within 30-60 minutes, and the therapeutic window lasts up to 4 hours.

Dapoxetine selectively blocks the reuptake of serotonin at central nervous system synapses, increasing serotonergic tone. Elevated serotonin delays the ejaculatory reflex, thereby extending the intravaginal ejaculation latency time (IELT). Dapoxetine’s short half-life (≈ 1.5 hours) limits systemic exposure, reducing the risk of prolonged serotonergic side effects.

In combination, sildenafil facilitates the mechanical aspect of sexual activity, while dapoxetine lengthens the duration of intercourse by postponing ejaculation. The two mechanisms act independently but synergistically, allowing many men to experience both a firm erection and a more satisfying ejaculation interval from a single dose.

Conditions Treated with Super P-Force

Both conditions frequently coexist; addressing them together reduces pill burden and may improve adherence.

Off-Label and Investigational Uses of Super P-Force

• Female sexual arousal disorder - Small pilot studies have examined sildenafil’s effect on genital blood flow in women, but benefits remain unproven and regulatory approval is absent. |
• Lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH) - Sildenafil, by relaxing smooth muscle in the bladder neck and prostate, has shown modest improvements in urinary flow in limited trials. |
• Psychogenic erectile dysfunction - Because dapoxetine modulates central serotonergic pathways, some clinicians explore its adjunctive role in cases where anxiety contributes to ED. |

These applications have not been formally approved by the FDA, EMA, or other major regulators. Any off-label use must be undertaken under the direct supervision of a qualified healthcare provider, with informed consent about the limited evidence base and potential risks.

Is Super P-Force the Right Medication for You?

Super P-Force is most appropriate for adult men who meet both of the following criteria:

1. A clinical diagnosis of erectile dysfunction that responds to PDE5 inhibition, and
2. A diagnosis of premature ejaculation (IELT < 1 minute) that is responsive to short-acting SSRI therapy.

Patients who have contraindications to either component-such as concomitant use of nitrates, severe cardiovascular disease, uncontrolled hypertension, or a history of serotonin syndrome-should not use this combination. Additionally, men with hypersensitivity to any excipients in the tablet formulation must avoid it.

In cases where only one of the two conditions is present, monotherapy with the appropriate single agent is generally preferred to minimize unnecessary drug exposure.

Risks, Side Effects, and Interactions

Common

• Headache
• Flushing
• Nasal congestion
• Dyspepsia (indigestion)
• Dizziness

These events are usually mild to moderate and resolve without medical intervention.

Rare

• Visual disturbances (e.g., blue-tinted vision, blurred vision)
• Auditory impairment (tinnitus or hearing loss)
• Priapism (prolonged erection lasting > 4 hours)

Patients experiencing any of these symptoms should seek prompt medical advice.

Serious

• Cardiovascular events (myocardial infarction, stroke) in patients with underlying heart disease
• Severe hypotension, especially when combined with nitrates or alpha-blockers
• Serotonin syndrome (agitation, hyperthermia, tremor, diaphoresis) when dapoxetine is taken with other serotonergic agents

If any serious reaction occurs, immediate emergency care is required.

Drug-Drug Interactions

• Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Co-administration can cause profound hypotension.
• Alpha-blockers (e.g., tamsulosin, doxazosin): May increase the risk of low blood pressure.
• Other PDE5 inhibitors: Additive effects can lead to excessive vasodilation.
• Serotonergic drugs (e.g., SSRIs, MAO inhibitors, tramadol, linezolid): Increase the risk of serotonin syndrome.
• CYP3A4 inhibitors (e.g., ketoconazole, erythromycin, grapefruit juice): May raise sildenafil plasma concentrations, increasing adverse-event risk.

Drug-Food Interactions

• Heavy, fatty meals: Can delay sildenafil absorption, reducing onset speed.
• Alcohol: Moderate consumption is generally tolerated, but excessive intake may worsen hypotension and dizziness.

Use: Dosing, Missed Dose, Overdose

Standard dosing: Adults take one tablet (100 mg sildenafil / 60 mg dapoxetine) approximately 30-60 minutes before anticipated sexual activity. The dose should not be repeated more than once within a 24-hour period.

Missed dose: If a dose is forgotten and sexual activity is still anticipated within the next 24 hours, the tablet may be taken as soon as remembered. If the 24-hour window has already passed, skip the missed dose and resume the regular schedule; do not double-dose.

Overdose: Symptoms of sildenafil overdose may include severe hypotension, prolonged erection, and cardiac arrhythmia. Dapoxetine overdose can present with nausea, vomiting, seizures, or serotonin syndrome. In suspected overdose, seek immediate medical attention or call emergency services. Activated charcoal may be considered if presentation is early, and supportive care is the mainstay of treatment.

Practical precautions:

• Do not take with nitrate-containing medication.
• Avoid consuming large amounts of alcohol within two hours of dosing.
• Refrain from operating heavy machinery or driving if dizziness occurs.
• Store tablets at 20-25 °C (68-77 °F) in a dry place, protected from light.

FAQ

• What should I do if I travel abroad with Super P-Force?

  • Keep the medication in its original packaging with the label visible. Carry a copy of the prescription or a doctor’s letter if required by customs. Store the tablets in a carry-on bag to avoid temperature extremes in checked luggage.

• Can the tablet be split or crushed?

  • The tablet is formulated for whole-tablet administration. Splitting or crushing may alter the release characteristics and affect efficacy. Use the tablet intact unless a healthcare professional advises otherwise.

• Does Super P-Force contain any allergens?

  • Inactive ingredients typically include lactose, microcrystalline cellulose, and magnesium stearate. Patients with severe lactose intolerance or known hypersensitivity should verify the full excipient list on the product insert.

• How long does it take for the medication to be cleared from the body?

  • Sildenafil has an average half-life of 4 hours, while dapoxetine’s half-life is about 1.5 hours. Both drugs are eliminated primarily via hepatic metabolism and renal excretion; most of the dose is cleared within 24 hours.

• Will taking Super P-Force affect routine blood tests?

  • Sildenafil and dapoxetine do not interfere with standard metabolic panels or lipid profiles. However, they may be detected in specialized drug-screening assays, so inform the laboratory if you are undergoing testing for occupational or legal reasons.

• Is it safe to use Super P-Force with antihypertensive medication?

  • Concurrent use is generally permissible, but blood pressure should be monitored, especially when initiating therapy. Consult a healthcare professional if you are on multiple antihypertensives or experience symptoms of hypotension.

• What is the difference between this combination and taking the two drugs separately?

  • The combined tablet ensures synchronized pharmacokinetics, reducing the need for two separate dosing times. Bioavailability is comparable to individual tablets, but the convenience may improve adherence.

• Can women use Super P-Force for sexual dysfunction?

  • The product is not approved for use in females. While sildenafil has been studied off-label for female arousal, the safety and efficacy of this specific combination in women have not been established.

• How should the medication be stored in hot climates?

  • Keep the tablet in a cool, dry place away from direct sunlight. If ambient temperatures exceed 30 °C (86 °F) for extended periods, consider storing the package in a climate-controlled area or using a insulated carrier.

• Is there any risk of dependence on dapoxetine?

  • Dapoxetine is a short-acting SSRI with a low potential for physical dependence. Nonetheless, long-term daily use should be monitored by a physician to assess efficacy and any emerging side effects.

• What should I do if I experience a mild headache after dosing?

  • Headaches are common and often resolve within a few hours. Over-the-counter analgesics such as acetaminophen can be used, provided they do not contain contraindicated ingredients. Persistent or severe headaches warrant medical evaluation.

Glossary

Phosphodiesterase-5 (PDE5) inhibitor

A drug class that blocks the PDE5 enzyme, preventing breakdown of cGMP and promoting smooth-muscle relaxation in the penis, which facilitates erection.

Selective serotonin-reuptake inhibitor (SSRI)

A medication that increases serotonin levels in the brain by inhibiting its reabsorption into nerve cells, commonly used to treat depression and, in short-acting forms like dapoxetine, premature ejaculation.

Intravaginal ejaculation latency time (IELT)

The measured interval between vaginal penetration and ejaculation; a key clinical endpoint in studies of premature ejaculation.

Serotonin syndrome

A potentially life-threatening condition caused by excessive serotonergic activity, characterized by agitation, hyperthermia, tremor, and autonomic instability.

Buying Super P-Force from Our Online Pharmacy

Patients who encounter limited availability or high out-of-pocket costs for combination sexual-dysfunction therapy can obtain Super P-Force through our online pharmacy. Our service sources the medication exclusively from licensed, GMP-certified manufacturers, ensuring that each tablet meets the same quality standards required by national regulatory agencies.

Because we operate as a pharmacy-broker platform, we can negotiate near-manufacturer pricing, which translates into lower retail costs for you. The pricing model is transparent, with no hidden mark-ups. Once an order is placed, the product is dispatched from a secure fulfillment center. Delivery options include a rapid 7-day express service for urgent needs and a standard international airmail route that typically arrives within three weeks. All shipments are packaged discreetly, with no external identifiers indicating the contents, to protect your privacy.

Our platform also provides verification of the product’s provenance, a clear expiration-date guarantee, and a dedicated support line for any logistical questions. By choosing our online pharmacy, you gain a reliable, confidential, and cost-effective way to access Super P-Force when conventional pharmacy channels are unavailable or financially burdensome.

Disclaimer

The information presented about Super P-Force is intended for general educational purposes only and does not substitute for professional medical advice. All therapeutic decisions, including those involving off-label applications, should be made under the direct supervision of a qualified healthcare professional. Readers are assumed to be competent adults capable of making informed choices regarding their health. Our online pharmacy provides a means to obtain Super P-Force for individuals who may encounter restricted access through traditional pharmacy networks, insurance-based dispensing systems, or who are seeking a more affordable generic alternative. Prior to initiating, altering, or discontinuing any medication, you must consult a licensed clinician.