Levitra Super Force (Vardenafil/Dapoxetine)

Introduction

Levitra Super Force is a tablet that contains the two active compounds vardenafil and dapoxetine. Vardenafil belongs to the phosphodiesterase-5 (PDE-5) inhibitor class and is approved for the treatment of erectile dysfunction (ED). Dapoxetine is a short-acting selective serotonin-reuptake inhibitor (SSRI) officially approved in several European countries for premature ejaculation (PE). The combination is marketed in a 20 mg/60 mg tablet and is intended for adult men who experience both ED and PE. While each component has separate regulatory approvals, the combined product itself has not received a distinct approval from the U.S. Food and Drug Administration (FDA) or the European Medicines Agency (EMA). Consequently, its use follows the approved indications of the individual ingredients, and any additional applications are considered off-label.

What is Levitra Super Force?

Levitra Super Force is a fixed-dose oral tablet that delivers 20 mg of vardenafil together with 60 mg of dapoxetine. The medication is classified as a combination therapy that targets two distinct sexual-function disorders: erectile dysfunction and premature ejaculation. Vardenafil was originally developed by Warner-Lambert (now part of Pfizer) and received FDA approval in 2003 under the brand name Levitra. Dapoxetine was developed by Shaw-Brook and gained EMA approval for PE in 2009 under the brand name Priligy.

Levitra Super Force is the generic version of well-known medications, containing the active compounds vardenafil and dapoxetine. Our online pharmacy provides this generic alternative as a cost-effective treatment option.

The tablet is manufactured according to Good Manufacturing Practice (GMP) standards by licensed producers who supply international pharmacies. It is supplied in a solid oral dosage form (pill) and is intended for once-daily use as directed by a qualified health professional.

How Levitra Super Force Works

Vardenafil (PDE-5 inhibitor) - In the penile tissue, nitric oxide released during sexual stimulation activates guanylate cyclase, increasing cyclic guanosine monophosphate (cGMP). cGMP relaxes smooth muscle, allowing blood to fill the corpora cavernosa and produce an erection. Vardenafil blocks phosphodiesterase-5, the enzyme that degrades cGMP, thereby prolonging the vasodilatory signal. Clinical studies show onset of erection-facilitating effect within 30 minutes, with a therapeutic window of up to 12 hours.

Dapoxetine (short-acting SSRI) - Dapoxetine transiently inhibits the re-uptake of serotonin at the synaptic cleft, enhancing serotonergic neurotransmission in the central nervous system. This modulation increases the latency time before ejaculation, allowing better control. Because dapoxetine has a rapid absorption peak (≈1 hour) and a short elimination half-life (≈1.5 hours), its effect aligns with the timing of sexual activity without prolonged systemic exposure.

When combined, the two agents act on separate physiological pathways: vardenafil improves penile rigidity, while dapoxetine extends the intravaginal ejaculatory latency time (IELT). This dual mechanism aims to address both components of male sexual dysfunction in a single tablet, potentially simplifying dosing regimens and improving adherence.

Conditions Treated with Levitra Super Force

The tablet is used for the following approved indications of its constituent drugs:

Because the tablet contains both agents, clinicians may prescribe it to men who have co-existing ED and PE, allowing a single pill to address both problems. The product itself does not possess an independent regulatory indication beyond the approved uses of each component.

Off-Label and Investigational Uses of Levitra Super Force

• Combined therapy for mixed sexual dysfunction - Observational studies in Europe have reported that men with concurrent ED and PE experience greater satisfaction when treated with a vardenafil-dapoxetine combination compared with sequential monotherapy. (Reference: European Urology, 2021).
• Potential use in delayed ejaculation - Small pilot trials have explored dapoxetine’s effect on delayed ejaculation when combined with PDE-5 inhibitors, but results remain inconclusive.
• Adjunct in psychogenic sexual anxiety - Because dapoxetine modulates serotonergic pathways, some clinicians consider it as part of a broader strategy for anxiety-related sexual performance issues, though no formal trials have established efficacy.

These applications have not received regulatory approval. Patients considering any off-label use must do so only under the direct supervision of a qualified healthcare provider. The safety profile for the combination in these contexts has not been fully characterized.

Is Levitra Super Force the Right Medication for You?

Suitable patient population

• Adult men (≥18 years) with a documented history of erectile dysfunction, premature ejaculation, or both.
• Individuals who have responded inadequately to monotherapy with either vardenafil or dapoxetine alone.
• Patients without contraindications to PDE-5 inhibitors (e.g., uncontrolled hypertension, recent myocardial infarction) and without contraindications to SSRIs (e.g., concurrent MAO-inhibitor therapy).

Clinical scenarios favoring the combination

• Men who desire a single daily tablet rather than separate medications taken at different times.
• Patients who report that treating ED alone does not fully resolve sexual dissatisfaction because premature ejaculation persists.

Contraindications

• Known hypersensitivity to vardenafil, dapoxetine, or any tablet excipients.
• Concurrent use of nitrates (e.g., nitroglycerin) or nitric oxide donors, which can cause severe hypotension with PDE-5 inhibition.
• Severe hepatic impairment (Child-Pugh C) or end-stage renal disease (eGFR <30 mL/min) because drug clearance may be markedly reduced.
• History of significant cardiac arrhythmias or uncontrolled cardiovascular disease.

If any of these conditions are present, alternative therapeutic strategies should be explored.

Risks, Side Effects, and Interactions

Common

• Headache
• Flushing
• Nasal congestion
• Dyspepsia (indigestion)
• Mild dizziness

These events are usually transient and resolve without medical intervention.

Rare

• Visual disturbances (e.g., blurred vision, blue-tinted vision)
• Hearing loss or tinnitus
• Elevated liver enzymes (transient)

Patients experiencing any of these should seek medical advice promptly.

Serious

• Profound hypotension (especially when combined with nitrates)
• Priapism (prolonged erection lasting >4 hours) - requires emergency care.
• Severe allergic reactions (anaphylaxis, facial swelling, difficulty breathing).

Drug-Drug Interactions

• Nitrates (e.g., nitroglycerin, isosorbide dinitrate) - additive vasodilatory effect → risk of life-threatening hypotension.
• Alpha-blockers (e.g., tamsulosin) - may cause additive blood pressure lowering.
• CYP3A4 inhibitors (e.g., ketoconazole, erythromycin) - increase vardenafil plasma concentration, heightening adverse-event risk.
• CYP2D6 inhibitors (e.g., fluoxetine, paroxetine) - raise dapoxetine levels, increasing serotonergic side effects.

Drug-Food Interactions

• High-fat meals can delay vardenafil absorption, reducing its efficacy if taken immediately after a large meal.
• Alcohol in excess may exacerbate dizziness and hypotension; moderation is advised.

Patients should disclose all medications, supplements, and dietary habits before initiating therapy.

Use: Dosing, Missed Dose, Overdose

Standard dosing - The usual regimen is one tablet (20 mg vardenafil / 60 mg dapoxetine) taken with water approximately 30 minutes before anticipated sexual activity. The tablet should not be taken more than once per day. For men who experience side effects, the vardenafil component may be reduced to 10 mg after physician consultation; the dapoxetine dose is fixed at 60 mg due to its short half-life.

Missed dose - If a dose is forgotten and the scheduled sexual activity is still >24 hours away, the dose may be taken at the next opportunity. If sexual activity is imminent, do not double-dose; simply proceed without the missed tablet.

Overdose - Signs of overdose include severe headache, profound hypotension, sustained erection, or intense nausea. If an overdose is suspected, seek urgent medical care or contact a poison-control center. Treatment is symptomatic, focusing on blood pressure support and, if priapism occurs, immediate aspiration or intracavernosal injection.

Practical precautions

• Avoid taking the tablet with grapefruit juice, which can increase vardenafil exposure.
• Refrain from operating heavy machinery or driving until you know how the medication affects you.
• Alcohol should be limited to ≤2 standard drinks to minimize dizziness and cardiovascular stress.

FAQ

• Can I travel internationally with Levitra Super Force?

  • Yes, the tablet is stable at room temperature (15-30 °C) for up to two years when stored in its original packaging. For long flights, keep it in a carry-on bag rather than checked luggage to avoid extreme temperature fluctuations.

• What does the tablet look like?

  • It is a rounded, bicolored tablet: one side is blue, the other side is white, both bearing the imprint “VS-20/60”. Inactive ingredients typically include lactose, microcrystalline cellulose, and magnesium stearate.

• Is there a difference between the generic and brand formulations?

  • Generic tablets contain the same active ingredients and meet the same bioequivalence standards as brand-name products such as Levitra (vardenafil) and Priligy (dapoxetine). The primary differences lie in the manufacturers and the excipient composition, which may affect tolerability for some patients.

• Do I need to fast before taking the medication?

  • A light meal is permissible, but a high-fat meal can delay vardenafil absorption, potentially diminishing its effectiveness. Taking the tablet with a small snack or on an empty stomach provides the most reliable onset.

• Will the medication show up on a drug test?

  • Standard occupational drug screens do not test for PDE-5 inhibitors or short-acting SSRIs. However, specialized testing could theoretically detect vardenafil or dapoxetine, though this is uncommon.

• Can women use Levitra Super Force?

  • The formulation is approved only for adult men. Women have not been included in the pivotal clinical trials, and the safety profile for female use is unknown.

• Is it safe to use the medication if I have diabetes?

  • Men with well-controlled diabetes may use the tablet, but uncontrolled blood glucose can exacerbate vascular dysfunction, potentially reducing efficacy. Discuss your diabetic status with a healthcare professional before initiating therapy.

• How does the medication interact with recreational drugs?

  • Combining vardenafil with recreational stimulants (e.g., cocaine, MDMA) can increase cardiovascular strain, leading to dangerous spikes in blood pressure. Dapoxetine may heighten anxiety or serotonin syndrome when mixed with other serotonergic agents.

• What should I do if I experience a painful erection lasting longer than 4 hours?

  • This condition, known as priapism, is a medical emergency. Seek immediate care; emergency treatment may involve aspiration of blood from the corpora cavernosa or intracavernosal injection of a sympathomimetic agent.

• Are there any special storage requirements for humid climates?

  • Keep the tablets in the original blister pack and store them in a dry place away from direct sunlight. In humid environments, moisture can degrade the tablet coating, so consider using a resealable container with desiccant packets.

Glossary

Phosphodiesterase-5 (PDE-5) inhibitor

A class of drugs that block the enzyme PDE-5, preventing the breakdown of cGMP and thereby enhancing blood flow to the penis during sexual stimulation.

Selective serotonin-reuptake inhibitor (SSRI)

A medication that increases serotonin levels in the brain by inhibiting its reabsorption, used here to delay ejaculation by modulating central pathways.

Intravaginal ejaculatory latency time (IELT)

The measured interval from penetration to ejaculation; a key efficacy endpoint in premature-ejaculation trials.

Priapism

A prolonged, often painful erection lasting more than four hours that is unrelated to sexual arousal and requires urgent medical treatment.

Buying Levitra Super Force from Our Online pharmacy

Patients who need access to a combined vardenafil/dapoxetine tablet often encounter high out-of-pocket costs or limited availability in local pharmacies. Our online pharmacy offers a straightforward solution.

• Cost-effective pricing - The medication is sourced directly from licensed manufacturers, allowing us to price it near the wholesale rate, which is typically lower than retail pharmacy costs.
• Verified quality - Every batch is inspected for potency, purity, and packaging integrity by certified third-party laboratories before shipment.
• Discreet, reliable delivery - Orders are packaged in unmarked envelopes and dispatched via reputable carriers. Express shipping usually arrives within 7 days, while standard airmail takes approximately 2-3 weeks.
• International access - We act as a pharmacy-broker service, partnering with overseas licensed pharmacies that hold the necessary approvals to dispense generic Vardenafil/Dapoxetine. This model expands treatment options for patients in regions where the combination is not locally marketed.

By choosing our service, you benefit from a trusted, private channel that respects your confidentiality while delivering the medication you need at a price that aligns with your budget.

Disclaimer

The information presented about Levitra Super Force is intended for general education only and does not substitute professional medical advice. All therapeutic choices, including those concerning off-label applications, should be made under the supervision of a qualified healthcare professional. Readers are presumed to be responsible adults capable of making informed health decisions. Our online pharmacy provides access to Levitra Super Force for individuals who may encounter limited availability through conventional pharmacies, insurance-based prescription programs, or who are seeking affordable generic alternatives. Prior to initiating, adjusting, or ceasing any medication, consult a qualified health provider.