Generic Fildena Professional (Sildenafil Citrate)

Introduction

Fildena Professional is a tablet that contains the active ingredient sildenafil citrate, a phosphodiesterase-5 (PDE-5) inhibitor approved for the treatment of erectile dysfunction (ED). It is supplied in a 100 mg dosage form and belongs to the class of oral vasodilators used to improve penile blood flow. The medication is also indicated for pulmonary arterial hypertension (PAH) under a different brand formulation. While its primary indication is ED, clinicians sometimes discuss off-label applications such as certain types of lower urinary-tract symptoms, but these uses have not received formal regulatory approval.

What is Fildena Professional?

Fildena Professional is the generic version of well-known medications, containing the active compound sildenafil citrate. Our online pharmacy provides this generic alternative as a cost-effective treatment option. The product is manufactured as a film-coated tablet that delivers a fixed 100 mg dose of sildenafil citrate. The medication is classified as a phosphodiesterase-5 inhibitor and was originally developed by Pfizer, where it was marketed under brand names such as Viagra for erectile dysfunction and Revatio for pulmonary arterial hypertension. The generic formulation follows the same pharmacological profile and therapeutic intent as the branded products.

How Fildena Professional Works

Sildenafil citrate blocks the enzyme phosphodiesterase-5, which normally degrades cyclic guanosine monophosphate (cGMP) in smooth-muscle cells of the penis and pulmonary vasculature. By inhibiting PDE-5, sildenafil elevates cGMP levels, leading to relaxation of smooth muscle and dilation of blood vessels. In the corpus cavernosum, this vasodilation allows increased arterial inflow, facilitating erection in response to sexual stimulation. In the pulmonary arteries, the same mechanism reduces vascular resistance, improving exercise capacity in PAH patients. Onset of action typically occurs within 30-60 minutes, with clinical effects lasting up to 4-6 hours. The drug is primarily metabolized by hepatic CYP3A4 and CYP2C9 enzymes and eliminated via feces and urine.

Conditions Treated with Fildena Professional

• Erectile Dysfunction (ED): Sildenafil improves erections by enhancing penile blood flow when sexual arousal occurs. It is indicated for men with difficulty attaining or maintaining sufficient penile rigidity for satisfactory sexual activity.
• Pulmonary Arterial Hypertension (PAH): In the Revatio formulation, the same molecule reduces pulmonary vascular resistance, improving functional class and exercise tolerance in adult patients with PAH.

These indications are approved by major regulatory agencies, including the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA). The medication’s efficacy in these conditions is supported by large-scale, randomized controlled trials demonstrating improvements in the International Index of Erectile Function (IIEF) scores for ED and six-minute walk distance for PAH.

Off-Label and Investigational Uses of Fildena Professional

• Benign Prostatic Hyperplasia (BPH)-related lower urinary-tract symptoms: Small studies have reported modest improvement in urinary flow rates when sildenafil is combined with α-blockers, likely due to pelvic vasodilation. Regulatory agencies have not approved this indication.
• Raynaud’s phenomenon: Preliminary case series suggest that sildenafil may reduce the frequency and severity of vasospastic attacks through peripheral vasodilation, but evidence remains limited.
• High-altitude pulmonary edema (HAPE): Experimental data from high-altitude research indicate that sildenafil can lower pulmonary artery pressure, potentially mitigating HAPE risk. This application is investigational and not approved for routine clinical use.

Patients should discuss any off-label consideration with a qualified healthcare provider, as safety and efficacy have not been formally established for these uses.

Is Fildena Professional the Right Medication for You?

Fildena Professional is appropriate for adult men diagnosed with erectile dysfunction who have sufficient cardiovascular health to tolerate sexual activity. It is also suitable for adults with pulmonary arterial hypertension when prescribed under appropriate clinical supervision. The medication should be considered when:

• The patient experiences consistent difficulty achieving or sustaining an erection despite sexual stimulation.
• The patient has been evaluated for contraindications such as recent myocardial infarction, uncontrolled hypertension, or severe hepatic impairment.
• The individual does not currently use nitrates or potent CYP3A4 inhibitors, which can cause dangerous drops in blood pressure.

Patients with severe visual disorders (e.g., non-arteritic anterior ischemic optic neuropathy), a history of priapism, or known hypersensitivity to sildenafil or any tablet excipients should avoid the drug.

Risks, Side Effects, and Interactions

Common

• Headache
• Flushing (warmth, redness of face or neck)
• Dyspepsia (indigestion)
• Nasal congestion
• Visual disturbances (blue-tinted vision, blurred vision)

Rare

• Myalgia or back pain (often related to increased prostaglandin activity)
• Dizziness or light-headedness, particularly when standing quickly
• Hearing loss or tinnitus
• Rash or mild urticaria

Serious

• Priapism (prolonged erection > 4 hours) - requires immediate medical attention to prevent tissue damage.
• Severe hypotension, especially when combined with nitrates or alpha-blockers.
• Cardiovascular events (myocardial infarction, stroke) in patients with pre-existing heart disease.
• Non-arteritic anterior ischemic optic neuropathy (NAION) leading to sudden vision loss.

Drug-Drug Interactions

• Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Co-administration can cause profound hypotension; contraindicated.
• Potent CYP3A4 inhibitors (e.g., ketoconazole, ritonavir): May increase sildenafil plasma concentrations, raising risk of adverse effects; dose reduction recommended.
• Alpha-blockers (e.g., tamsulosin): Can lead to additive blood-pressure lowering; monitor closely.

Drug-Food Interactions

• High-fat meals can delay absorption, reducing the speed of onset.
• Moderate alcohol intake may enhance vasodilatory effects and increase the likelihood of hypotension or dizziness.

Patients should always disclose all medications, supplements, and significant dietary habits to their prescriber.

Use: Dosing, Missed Dose, Overdose

• Standard dosing: For most men, a single 100 mg tablet taken with water approximately 30-60 minutes before sexual activity is appropriate. The dose may be reduced to 50 mg or increased to 100 mg based on efficacy and tolerability, but should not exceed one tablet per day.
• Missed dose: Sildenafil is taken only as needed; there is no scheduled daily dosing. If a dose is missed, it can be taken later the same day provided at least 12 hours have elapsed since the previous dose. Do not take an additional tablet to “make up” for a missed dose.
• Overdose: Symptoms may include severe hypotension, prolonged erection, chest pain, or fainting. If overdose is suspected, seek immediate medical care; supportive measures such as intravenous fluids and blood pressure monitoring are typical.

Practical precautions

• Avoid taking sildenafil with grapefruit juice, which can inhibit CYP3A4 metabolism.
• Do not operate heavy machinery or drive if you experience dizziness or visual changes.
• Alcohol in excess may amplify side effects; limit intake to moderate levels.

FAQ

• What should I do if I experience a prolonged erection after taking Fildena Professional? If an erection lasts longer than four hours, seek emergency medical care promptly to prevent permanent tissue damage.

• Can I take Fildena Professional if I have high blood pressure? Controlled hypertension is not a contraindication, but uncontrolled high blood pressure may increase the risk of cardiovascular events. Consult a healthcare professional for individualized assessment.

• Is it safe to use Fildena Professional with antihypertensive medications? Yes, in most cases, but caution is advised when combined with alpha-blockers or nitrates due to additive blood-pressure lowering effects.

• How does food affect the absorption of Fildena Professional? A high-fat meal can delay absorption, possibly reducing the rapidity of the onset. Taking the tablet on an empty or lightly fed stomach may provide a more predictable effect.

• Will Fildena Professional cause permanent changes in sexual desire? Sildenafil affects the physiological response to sexual stimulation but does not alter libido directly. Changes in desire are usually related to psychological or hormonal factors.

• What are the inactive ingredients in the 100 mg tablet? Common excipients include microcrystalline cellulose, croscarmellose sodium, magnesium stearate, and a film-coating polymer. Exact composition can vary by manufacturer.

• Can I travel internationally with Fildena Professional? Yes, but keep the medication in its original packaging, carry a copy of the prescription (if required), and be aware of the importing country's regulations regarding sildenafil.

• Does Fildena Professional affect drug testing for employment or sports? Standard drug screens do not detect sildenafil, as it is not a controlled substance. However, specialized testing for PDE-5 inhibitors exists for anti-doping purposes.

• Is there a difference between taking Fildena Professional and the branded Viagra? The generic and branded products contain the same active molecule, dosage strength, and clinical efficacy. Differences may exist in inactive ingredients or tablet appearance, which generally do not affect therapeutic outcome.

• Can elderly patients safely use Fildena Professional? Older adults may have slower drug clearance and are more likely to use concurrent medications. Starting at a lower dose (e.g., 50 mg) and titrating based on response is recommended.

• What should I do if I accidentally take two tablets at once? Monitor for symptoms such as severe headache, dizziness, or a prolonged erection. If any serious effects occur, seek medical attention immediately.

• Are there any herbal supplements that interact with sildenafil? Herbal products containing nitrates (e.g., certain vasodilatory supplements) or strong CYP3A4 inhibitors (e.g., grapefruit seed extract) may increase the risk of hypotension.

• How long can I store Fildena Professional before it expires? The tablet is stable for 24 months when stored at room temperature (15-30 °C) in a dry place, away from direct sunlight. Check the printed expiration date on the packaging.

Glossary

Phosphodiesterase-5 (PDE-5) Inhibitor

A class of drugs that block the enzyme PDE-5, increasing cGMP levels and promoting smooth-muscle relaxation in the penis and pulmonary arteries.

cGMP (Cyclic Guanosine Monophosphate)

A secondary messenger molecule that mediates vasodilation; higher concentrations lead to relaxed blood vessels.

Priapism

A prolonged, often painful erection lasting more than four hours, requiring urgent medical intervention to avoid tissue damage.

Buying Fildena Professional from Our Online Pharmacy

Patients seeking an affordable, reliable source of sildenafil citrate can obtain Fildena Professional through our online pharmacy. By partnering with licensed overseas suppliers, the pharmacy broker service ensures that each tablet meets stringent quality standards and originates from reputable manufacturers.

• Cost-effectiveness: Generic pricing is close to the manufacturing cost, offering substantial savings compared with branded options.
• Verified authenticity: All batches are sourced from verified, licensed distributors, reducing the risk of counterfeit medication.
• Discreet delivery: Packages are shipped in unmarked, secure packaging, protecting your privacy throughout the fulfillment process. Typical shipping times range from 7 days for express service to about 3 weeks for standard airmail, depending on the destination.
• Easy access: For individuals who encounter limited availability in local pharmacies or face insurance coverage gaps, the online platform provides a straightforward alternative without compromising safety.

By choosing this service, patients can address cost and accessibility concerns while maintaining confidence in the medication’s quality and confidentiality.

Disclaimer

The information presented about Fildena Professional is intended for general educational purposes and does not substitute professional medical advice. Treatment choices, including any off-label application, should be made under the supervision of a qualified healthcare provider. Readers are presumed to be responsible adults capable of making informed health decisions. Our online pharmacy offers access to Fildena Professional for individuals who may encounter limited availability through conventional pharmacies or who are seeking cost-saving generic alternatives. Always discuss with a medical professional before starting, modifying, or stopping any medication.