--- title: Buy Soriatane (Acitretin) 10mg Pills Online description: Soriatane (Acitretin) 10mg Pills is a trusted treatment for severe psoriasis and skin disorders. Order from our secure pharmacy for reliable delivery. type: product language: en url: https://medsforsale.net/buy-soriatane-online-en availability: in_stock price_min: 179.99 price_max: 651.99 currency: USD offers: - name: 10mg x 30 pills price: 179.99 - name: 10mg x 60 pills price: 338.99 - name: 10mg x 90 pills price: 499.99 - name: 10mg x 120 pills price: 651.99 --- # Buy Soriatane (Acitretin) 10mg Pills Online Soriatane, containing the active ingredient Acitretin, is a retinoid medication used to treat severe skin diseases such as psoriasis. This treatment works by allowing normal growth and development of skin cells and was originally developed by Hoffmann-La Roche. It is specifically used by adults who have not responded to other treatments for skin thickening and scaling. You can purchase Soriatane from our pharmacy in 10mg pills for your convenient home delivery. ## Pricing and Options | Dosage | Pack Size | Price (USD) | Price Per Pill | Status | | :--- | :--- | :--- | :--- | :--- | | **10mg** | 30 pills | **$179.99** | $6.00 | In Stock | | **10mg** | 60 pills | **$338.99** | $5.65 | In Stock | | **10mg** | 90 pills | **$499.99** | $5.56 | In Stock | | **10mg** | 120 pills | **$651.99** | $5.43 | In Stock | [Buy Now](https://medsforsale.net/buy-soriatane-online-en) ## Introduction Soriatane is a prescription-only oral medication used primarily for severe psoriasis and other keratinization disorders. Its active ingredient is acitretin, a synthetic retinoid that modifies skin cell growth. The drug is supplied as 10 mg tablets and belongs to the class of second-generation retinoids. Soriatane is indicated for adult patients with chronic plaque psoriasis that has not responded adequately to topical therapies, phototherapy, or conventional systemic agents. It is also approved for certain severe ichthyoses. Although the product is marketed under the Soriatane name, the same compound is available as generic acitretin, and comparable formulations are sold under brand names such as Absorica and Neotigason. In addition to its labeled uses, clinicians sometimes consider acitretin for select off-label conditions after weighing the evidence and safety profile. ## What is Soriatane? Soriatane contains the active compound acitretin, a pharmacologically active retinoid structurally related to vitamin A. It is manufactured by Bayer AG and distributed in many countries as a 10 mg oral tablet. The medication is classified as a systemic retinoid, a subgroup of the broader retinoid family that includes isotretinoin and alitretinoin. Acitretin was first synthesized in the 1970s and received regulatory approval in the early 1990s for the treatment of severe psoriasis. In the United States and Europe it is listed under the trade name Soriatane, while other markets use alternative brand names such as Absorica (Pfizer) and Neotigason (Mylan). ## How Soriatane Works Acitretin exerts its therapeutic effect by binding to nuclear retinoic acid receptors (RARα, RARβ, RARγ) and retinoid X receptors (RXR). Activation of these transcription factors normalizes the differentiation and proliferation of keratinocytes, the primary cells of the epidermis. In psoriasis, abnormal keratinocyte turnover leads to thick, scaly plaques; acitretin reduces this hyperproliferation and promotes a more orderly maturation process. The drug also exhibits anti-inflammatory properties by down-regulating cytokines such as interleukin-6 and tumor necrosis factor-α. Pharmacokinetic studies show that acitretin is well absorbed after oral administration, reaches peak plasma concentrations within 2-4 hours, and has a long elimination half-life of 49-70 days due to extensive enterohepatic recirculation. Because of this prolonged clearance, steady-state concentrations are typically achieved after 4-6 weeks of daily dosing. ## Conditions Treated with Soriatane - **Chronic Plaque Psoriasis (severe)** - Soriatane reduces plaque thickness, erythema, and scaling when topical agents and phototherapy are insufficient. Its systemic action addresses widespread disease that may involve the scalp, elbows, and knees. - **Pustular Psoriasis** - The drug can control the rapid formation of sterile pustules by modulating keratinocyte turnover and inflammatory pathways. - **Erythrodermic Psoriasis** - In this life-threatening variant, acitretin helps re-establish epidermal integrity and reduces systemic inflammation. - **X-linked Ichthyosis and Other Severe Ichthyoses** - By correcting the abnormal desquamation process, acitretin improves skin texture and reduces scaling. Each approved indication shares a common pathophysiology of excessive keratinocyte proliferation, which acitretin directly targets through its retinoid receptor activity. ## Off-Label and Investigational Uses of Soriatane - **Cutaneous T-cell Lymphoma (CTCL)** - Small case series have reported partial remission in early-stage Mycosis fungoides when combined with other systemic agents. This use remains investigational and has not received regulatory approval. - **Lichen Planus** - Retinoids, including acitretin, have been evaluated in uncontrolled studies that suggest improvement in hyperkeratotic lesions. Evidence is limited and safety must be monitored closely. - **Acne Conglobata** - Though isotretinoin is the standard retinoid for severe nodulocystic acne, some dermatologists have used acitretin off-label when isotretinoin is contraindicated. Clinical data are sparse. These off-label applications are based on limited clinical observations or early-phase trials. They have not undergone the rigorous efficacy and safety evaluation required for official approval. Patients should discuss any off-label consideration with a qualified healthcare provider before initiating therapy. ## Is Soriatane the Right Medication for You? Soriatane is most suitable for adult patients (≥18 years) with moderate-to-severe psoriasis or ichthyosis who have not achieved adequate control with topical treatments, phototherapy, or conventional systemic drugs such as methotrexate or cyclosporine. The medication is especially valuable when rapid disease control is needed and the patient can adhere to strict monitoring requirements. Contraindications include: - Pregnancy or planned conception (acquired teratogenicity). - Active liver disease or persistent elevation of hepatic enzymes. - Renal insufficiency with creatinine clearance <30 mL/min. - Uncontrolled hyperlipidaemia, as acitretin can raise triglyceride levels. - Known hypersensitivity to acitretin or any excipients in the tablet. Patients with a history of depression, severe osteoporosis, or those taking concomitant teratogenic drugs should be evaluated carefully before starting therapy. ## Risks, Side Effects, and Interactions ### Common - **Dry skin, lips, and mucous membranes** - Xerosis is reported in >30 % of patients and may be managed with emollients. - **Elevated triglycerides and cholesterol** - Lipid profiles should be monitored baseline and periodically during treatment. - **Mild musculoskeletal pain** - Arthralgia or myalgia may appear early in therapy. ### Rare - **Elevated liver enzymes** - Hepatotoxicity occurs in <5 % of users; routine liver function tests are recommended. - **Hair thinning or loss** - Reversible alopecia has been documented but is infrequent. ### Serious - **Severe hypertriglyceridaemia** - Levels >500 mg/dL increase pancreatitis risk and require immediate medical attention. - **Teratogenicity** - Acitretin is highly teratogenic; pregnancy must be avoided for at least 3 years after discontinuation. - **Bone demineralisation** - Long-term use may reduce bone mineral density, especially in post-menopausal women. #### Drug-Drug Interactions - **Tetracyclines, phenobarbital, carbamazepine** - Accelerate acitretin metabolism, potentially lowering efficacy. - **Vitamin A supplements** - Additive risk of hypervitaminosis A and related toxicity. - **Systemic corticosteroids** - May increase risk of skeletal abnormalities when combined with retinoids. #### Drug-Food Interactions - **Alcohol** - Should be avoided throughout therapy and for at least 2 years after stopping acitretin because alcohol can convert acitretin to etretinate, a compound with an even longer half-life and heightened teratogenic potential. Patients must inform their healthcare team of all concomitant medications, supplements, and alcohol consumption patterns. ## Use: Dosing, Missed Dose, Overdose Standard adult dosing of Soriatane begins at 25 mg per day (often administered as two 10 mg tablets plus a 5 mg capsule) and may be titrated up to 50 mg daily based on clinical response and tolerability. The lowest effective dose should be maintained to minimise adverse effects. - **Missed Dose** - If a dose is forgotten within 12 hours, take it as soon as remembered. If more than 12 hours have passed, skip the missed dose and resume the regular schedule. Do not double-dose. - **Overdose** - Acute ingestion of large amounts may cause severe hyperlipidaemia, hepatotoxicity, and mucocutaneous toxicity. Seek emergency medical care immediately; treatment is supportive and may include activated charcoal if presentation is early. Soriatane should be taken with a full glass of water, preferably with food to reduce gastrointestinal irritation. Patients should avoid operating heavy machinery until they know how the drug affects them, as dizziness and visual changes have been reported. ## FAQ - ****Can I travel internationally with Soriatane?** - Yes, but carry a copy of the prescribing information and the original pharmacy label. Some countries require a medical certificate for retinoids due to their teratogenic risk. - ****What does a Soriatane tablet look like?** - The 10 mg tablets are round, white, and film-coated with the imprint “10 mg ACIT”. In certain markets the tablet color and imprint may differ slightly, but the strength and inactive ingredients remain consistent. - ****Are there any sugar or gluten ingredients in the formulation?** - In most regions the tablet contains lactose as a filler and does not contain added sugar or gluten. Patients with severe lactose intolerance should confirm with the supplier. - ****How should I store Soriatane in hot climates?** - Keep the tablets in a dry place at a temperature not exceeding 30 °C (86 °F). If ambient temperature is higher, store the medication in a refrigerator (2-8 °C) away from moisture, but allow it to reach room temperature before ingestion. - ****Does Soriatane affect pregnancy tests?** - No direct interference is known, but the drug’s teratogenicity mandates strict contraception; a false-negative result could have serious consequences. - ****Can Soriatane be taken with hormonal contraceptives?** - Yes, combined oral contraceptives are recommended as part of the mandatory contraception program for women of child-bearing potential. - ****What is the shelf life after opening the bottle?** - Unopened tablets retain full potency for 24 months from the manufacture date. Once the bottle is opened, use the product within 12 months if stored under recommended conditions. - ****Is urine testing affected by taking Soriatane?** - Routine drug screens do not detect acitretin. However, specialized tests can identify retinoid metabolites, which may be relevant for certain occupational health screenings. - ****How does Soriatane differ from isotretinoin?** - Both are retinoids, but acitretin has a longer half-life and is primarily indicated for keratinization disorders, whereas isotretinoin is approved for severe acne. Their side-effect profiles overlap, yet acitretin is more strongly associated with lipid alterations and skeletal changes. - ****Can I switch from brand-name Soriatane to generic acitretin?** - Yes, the generic contains the same active molecule at equivalent strength. Bioequivalence studies show comparable efficacy and safety. Patients should discuss any switch with their prescriber to ensure appropriate monitoring continues. ## Glossary **Retinoid** : A class of compounds chemically related to vitamin A that influence cell growth, differentiation, and immune function. **Teratogenicity** : The capacity of a substance to cause birth defects when exposure occurs during pregnancy. **Enterohepatic Recirculation** : A process where a drug is secreted into bile, passes into the intestine, and is reabsorbed back into the bloodstream, prolonging its half-life. **Hypertriglyceridaemia** : An abnormally high level of triglycerides in the blood, which can increase the risk of pancreatitis. ## Buying Soriatane from [our online pharmacy](https://medsforsale.net/buy-soriatane-online-en) Soriatane can be obtained conveniently through [our online pharmacy](https://medsforsale.net/buy-soriatane-online-en). We source the medication directly from licensed, verified suppliers, ensuring that each batch meets strict quality standards comparable to manufacturer specifications. Because we operate as a pharmacy broker service, we can offer the generic acitretin formulation at a price close to the international reference cost, helping patients avoid the premium often charged by local retail pharmacies. Our delivery network provides discreet packaging and reliable shipping options, typically within 7 days for express service or approximately three weeks for standard airmail. The ordering process is fully online, safeguarding patient privacy while delivering the medication directly to the address you specify. For individuals facing limited access through conventional pharmacies or insurance formularies, our service presents a secure, cost-effective alternative to obtain the treatment they need. ## Disclaimer The information presented about Soriatane is intended solely for general educational purposes and does not substitute for professional medical advice. Treatment choices, including any off-label applications, must be made under the guidance of a qualified healthcare professional. Readers are presumed to be competent adults capable of making informed health decisions. [our online pharmacy](https://medsforsale.net/buy-soriatane-online-en) supplies Soriatane to persons who may encounter restricted availability via conventional pharmacies or insurance programs, or who seek an affordable generic alternative. Always discuss initiation, dosage adjustments, or discontinuation of any medication with your physician.